Music has been used to regulate emotions for perhaps millennia. From a parent’s soothing song to the ubiquitous iPod, humans continue to effectively use this powerful medium as a tool that one might call a medicine for emotion regulation. From the standpoint of evolution, it may have supported our survival as a species. For example, an infant who was soothed by the maternal lullaby would have been healthier due to a calmer state and improved sleep. This theory is supported by current research on the use of music for the stated purpose. An expansion of the evolutionary precursor with a brief review of two recent studies on this topic will be presented.