Prohibition of non-medical use of psilocybin, LSD, and other psychedelics was based on case reports and worst-case scenarios, rather than objective, evidence-based assessment of the risk of harm per user. Today, the expert consensus is that psilocybin and LSD are much less harmful than alcohol to the individual user. How can we communicate about risk to the general public, to courts, and to policy makers? I will present evidence from the Netherlands and the US on risks of psilocybin and LSD, share insights from the fields of risk assessment and risk communication, and answer some common questions about risk of psychedelics.