Stan Grofs and others work documented that our memory, either on genetic or epigenetic level surpasses all our previous expectations. How far can we get with the help or rigorous training in classical disciplines of sutrayana, mahayana, vajrayana and dzogchen in the view of modern neuroscience? Can we succeed and understand pivotal point of instant presence in the veiw of brain structure on its gross and cellular level? How are sensory inputs to the brain linked to the corresponding sensory memories and how are these explained in traditional buddhist canon? What are specific exercises on the physical level that enable us to uncover deepest declarative and procedural memories affecting our daily life? Good news is that we do not have to use chemical substances to undergo this, since modern brain science and traditional buddhist approaches are in this era all available together!