When presented with Out-of-Distribution (OOD) examples, deep neural networks yield confident, incorrect predictions. Detecting OOD examples is challenging, and the potential risks are high. In this paper, we propose to detect OOD examples by identifying inconsistencies between activity patterns and predicted class. We find that characterizing activity patterns by Gram matrices and identifying anomalies in Gram matrix values can yield high OOD detection rates. We identify anomalies in the Gram matrices by simply comparing each value with its respective range observed over the training data. Unlike many approaches, this can be used with any pre-trained softmax classifier and neither requires access to OOD data for fine-tuning hyperparameters, nor does it require OOD access for inferring parameters. We empirically demonstrate applicability across a variety of architectures and vision datasets and, for the important and surprisingly hard task of detecting far out-of-distribution examples, it generally performs better than or equal to state-of-the-art OOD detection methods (including those that do assume access to OOD examples).