Antibodies are immune system proteins that protect the host by binding to specific antigens such as viruses and bacteria.The binding between antibodies and antigens are mainly determined by the complementarity-determining regions (CDR) on the antibodies. In this work, we develop a deep generative model that jointly models sequences and structures of CDRs based on diffusion processes and equivariant neural networks. Our method is the first deep learning-based method that can explicitly target spe…